Pharmacy to Dose: The Critical Care Podcast

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Play-In Game/First Four Matchup Preview

#16 REVISE “Stress ulcer prophylaxis during invasive mechanical ventilation”
Pubmed Link
v.
#16 TGC-FAST “Tight blood-glucose control without early parenteral nutrition in the ICU”
Pubmed Link

First Round Matchup Preview

#1 RECOVERY “Dexamethasone in hospitalized patients with covid-19”
Pubmed Link
v.
#16 Play-In Winner (REVISE v. TGC-FAST)

#8 DEXA-ARDS “Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial”
Pubmed Link
v
#9 CLOVERS “Early restrictive or liberal fluid management for sepsis-induced hypotension”
Pubmed Link

#5 ACT “Intravenous tenecteplase compared with alteplase for acute ischemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial”
Pubmed Link
v.
#12 INTERACT3 “The third intensive care bundle with blood pressure reduction in acute cerebral hemorrhage trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial”
Pubmed Link

#4 CAPE COD “Hydrocortisone in severe community-acquired pneumonia”
Pubmed Link
v.
#13 TTM2 “Hypothermia versus normothermia after out-of-hospital cardiac arrest”
Pubmed Link

#6 MENDS2 “Dexmedetomidine or propofol for sedation in mechanically ventilated adults with sepsis”
Pubmed Link
v.
#11 AID-ICU “Haloperidol for the treatment of delirium in ICU patients”
Pubmed Link

#3 BLING III “Continuous vs intermittent beta-lactam antibiotic infusions in critically ill patients with sepsis: the BLING III randomized clinical trial”
Pubmed Link
v.
#14 PROCOAG “Efficacy and safety of early administration of 4-factor prothrombin complex concentrate in patients with trauma at risk of massive transfusion: the PROCOAG randomized clinical trial”
Pubmed Link

#7 DanGer Shock “Microaxial flow pump or standard care in infarct-related cardiogenic shock”
Pubmed Link
v.
#10 DOREMI “Milrinone as compared with dobutamine in the treatment of cardiogenic shock”
Pubmed Link

#2 ACORN “Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection: the ACORN randomized clinical trial”
Pubmed Link
v
#15 ANNEXA-I “Andexanet for factor xa inhibitor-associated acute intracerebral hemorrhage”
Pubmed Link