Pharmacy to Dose: The Critical Care Podcast

Lauren Igneri, PharmD, BCPS, BCCCP, FCCM joins as we debate the best thrombolytic dosing regimen in PE: full v. reduced-dose alteplase.

Nick – Full dose: 100mg alteplase

Lauren – Reduced dose: </= 50mg alteplase

Using one landmark trial to help make our argument, we debate in 3 specific situations:

1. High-risk PE
2. Intermediate-risk PE
3. Cardiac arrest

With a bonus round, comparing Tenecteplase to Alteplase to determine which is our thrombolytic of choice.

We review MOPETT, MAPPETT 3, PEAPETT, TROICA, PEITHO and 2 articles featuring Pharmacist authors!

Vote for who you think won this Versus series episode on Twitter/X @PharmacyToDose