Rapid reaction episode discussing the PROCOAG study looking at 4-factor prothrombin complex concentrate (PCC) use in trauma patients at risk of massive transfusion published in JAMA. We go into the outcomes, European v. American trauma management, PCC dosing, effect of viscoelastic testing, and much more.
Special guest: Scott Dietrich, PharmD, BCCCP
PROCOAG trial: https://pubmed.ncbi.nlm.nih.gov/36942533/
Reference List: https://pharmacytodose.files.wordpress.com/2023/04/procoag-rapid-reaction-references.pdf
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Pharmacy to Dose: The Critical Care Website 