Pharmacy to Dose: The Critical Care Podcast

Download and fill out your full bracket today!

Play-In Game/First Four Matchup

#13 NASCIS 2 “A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury”
Pubmed Link
v.
#13 “Propofol vs. midazolam in short-, medium-, and long-term sedation of critically ill patients: a cost-benefit analysis”
Pubmed Link

First Round Matchups

#1 NINDS “Tissue plasminogen activator for acute ischemic stroke”
Pubmed Link
v.
#16 “A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation”
Pubmed Link

#8 “A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures”
Pubmed Link
v.
#9 Nimodipine in aSAH studies (1983 NEJM & 1989 BMJ)

#5 “Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis”
Pubmed Link
v.
#12 “Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial”
Pubmed Link

#4 ISIS-2 “Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2”
v.
#13 Play-In Game Winner (NASCIS 2 v. Sedation Cost Analysis)

#6 “Risk factors for gastrointestinal bleeding in critically ill patients”
Pubmed Link
v.
#11 “Sclerotherapy with or without octreotide for acute variceal bleeding”
Pubmed Link

#3 “A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma”
Pubmed Link
v.
#14 “A comparison of four treatments for generalize convulsive status epilepticus”
Pubmed Link

#7 CAST “Mortality and morbidity in patients receiving encainide, flecainide, or placebo: The Cardiac Arrhythmia Suppression Trial”
Pubmed Link
v.
#10 GUSTO “An international, randomized trial comparing four thrombolytic strategies for acute myocardial infarction”
Pubmed Link

#2 TRICC “A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care”
Pubmed Link
v.
#15 “A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation”
Pubmed Link